Originally published in 1989, Reclaiming Reality still provides the most accessible introduction to the increasingly influential multi-disciplinary and international body of thought, known as critical realism. It is designed to "underlabour" both for the sciences, especially the human sciences, and for the projects of human emancipation which such sciences may come to inform; and provides an enlightening intervention in current debates about realism and relativism, positivism and poststucturalism, modernism and postmodernism, etc. Elaborating his critical realist perspective on society, nature, science (...) and philosophy itself, Roy Bhaskar shows how this perspective can be used to undermine currently fashionable ideologies of the Right, and at the same time, to clear the ground for a reinvigorated Left. Reclaiming Reality contains powerful critiques of some of the most important schools of thought and thinkers of recent years—from Bachelard and Feyerabend to Rorty and Habermas; and it advances novel and convincing resolutions of many traditional philosophical problems. Now with a new introduction from Mervyn Hartwig, this book continues to provide a straightforward and stimulating introduction to current debates in philosophy and social theory for the interested lay reader and student alike. Reclaiming Reality will be of particular value not only for critical realists but for all those concerned with the revitalization of the socialist emancipatory project and the renaissance of the Marxist theoretical tradition. Roy Bhaskar is the originator of the philosophy of critical realism, and the author of many acclaimed and influential works including A Realist Theory of Science, The Possibility of Naturalism, Scientific Realism and Human Emancipation and Dialectic: The Pulse of Freedom. He is an editor of the recently published Critical Realism: Essential Readings and is currently chair of the Centre for Critical Realism. (shrink)

ABSTRACT:Global multi-stakeholder initiatives are important instruments that have the potential to improve the social and environmental sustainability of global supply chains. However, they often fail to comprehensively address the needs and interests of various supply-chain participants. While voluntary in nature, MSIs have most often been implemented through coercive approaches, resulting in friction among their participants and in systemic problems with decoupling. Additionally, in those cases in which deliberation was constrained between and amongst participants, collaborative approaches have often failed to materialize. (...) Our framework focuses on two key aspects of these breakdowns: assumptions about the orientation of MSI participants, and the deliberation processes that participants use to engage with each other to create these initiatives and sustain them over time. Drawing from stakeholder and deliberation theories, we revisit the concept of MSIs and show how their deliberative capacity may be enhanced in order to encourage participants to collaborate voluntarily. (shrink)

Poor working conditions remain a serious problem in supplier facilities in developing countries. While previous research has explored this from the developed buyers’ side, we examine this phenomenon from the perspective of developing countries’ suppliers and subcontractors. Utilizing qualitative data from a major knitwear exporting cluster in India and a stakeholder management lens, we develop a framework that shows how the assumptions of conventional, buyer-driven voluntary governance break down in the dilution of buyer power and in the web of factors (...) rooted in suppliers’ traditions, beliefs, local demands and resource dependency. We reveal out how success in governing collaborative global supply chains often falls short within the subcontracting stage, where a stakeholder management mindset is elusive to most participants. We suggest that success in governing collaborative global supply chains is dependent on concepts of stakeholder utility and the presence of shared value that is often at odds with the realities of power, information asymmetry and compliance/reward systems inherent in the non-market coordination of global supply chains. Our findings offer important insights for delineating the concepts of value creation from CSR concepts and practices, and for modifying the basic assumptions of conventional supply chain governance. (shrink)

The Vedanta of conciousness : transcendence, enlightenment and everyday life -- The alienated self and the Kabbala of transformation -- The Zen of creativity and the critique of the discursive intellect -- The Tao of love and unconditionality in commitment -- The yoga of action and effortless efficiency -- The nous of perception and the re-enchantment of the tree of life -- The gnosis of freedom and the Fana of fulfilment.

This paper surveys the state-of-the-art in machine ethics, that is, considerations of how to implement ethical behaviour in robots, unmanned autonomous vehicles, or software systems. The emphasis is on covering the breadth of ethical theories being considered by implementors, as well as the implementation techniques being used. There is no consensus on which ethical theory is best suited for any particular domain, nor is there any agreement on which technique is best placed to implement a particular theory. Another unresolved problem (...) in these implementations of ethical theories is how to objectively validate the implementations. The paper discusses the dilemmas being used as validating ‘whetstones’ and whether any alternative validation mechanism exists. Finally, it speculates that an intermediate step of creating domain-specific ethics might be a possible stepping stone towards creating machines that exhibit ethical behaviour. (shrink)

Although there is such a thing as Indian thought, it seems to play no role in the way social sciences and philosophy are practiced in India or elsewhere. The problem is not only that we no longer employ terms such as atman, avidya, dharma to reflect on our experience; the terms that we do indeed use—sovereignty, secularism, rights, civil society and political society, corruption—seem to insulate our experience from our reflection. This paper will outline Gandhi’s framing of our predicament in (...) Hind Swaraj. It will then discuss three very different examples taken from our peculiar life with concepts that will also serve to clarify and illustrate the framework I am outlining. It will then very briefly discuss how Gandhi saw the Gita as showing him a way out of the predicament. (shrink)

During the 1980s and 1990s, the debate on the Marxist theory of history centred largely around the work of Robert Brenner’s property-relations-centred construal of it, and G.A. Cohen’s attempt to revive the classical, determinist argument. This article examines two influential arguments by Erik Wright and his colleagues, and by Alan Carling, which acknowledge important weaknesses in Cohen’s work, but which also try to construct a more plausible version of his theory. I show that the attempts to rescue Cohen are largely (...) unsuccessful. And, to the extent that they render the argument plausible, they do so at the cost of turning it, willy-nilly, into a kind of class-struggle theory. I conclude that this spells the demise of the classical version of historical materialism, but also observe that this does not leave us with a voluntaristic understanding of history, as some of its defenders fear. (shrink)

_Dialectic_ is now widely regarded as a classic of contemporary philosophy. This book, first published in 1993, sets itself three main aims: the development of a general theory of dialectic, of which Hegelian dialectic can be seen to be a special case; the dialectical enrichment and deepening of critical realism, viz. into the system of dialectical critical realism; and the outline of the elements of a totalizing critique of Western philosophy. The first chapter clarifies the rational core of Hegelian dialectic. (...) Chapter two then proceeds to develop a general theory of dialectic. Isolating the fallacy of 'ontological monovalence', Roy Bhaskar then shows how absence and other negating concepts such as contradiction have a legitimate and necessary ontological employment. He then goes on to give a synoptic account of key dialectical concepts such as the concrete universal; to sketch the further dialectical development of critical naturalism through an account of what he calls four-planar social being; and following consideration of the dialectical critique of analytical reason, he moves on to the real definition of dialectic as absenting absence and in the human sphere, the axiology of freedom. Chapter three extends and deepens critical realism’s characteristic concerns with ontology, science, social science and emancipation not only into the realms of negativity and totality, but also into the fields of reference and truth, spatio-temporality, tense and process, the logic of dialectical universalizability and on to the plane of ethics, where it articulates a combination of moral realism and ethical naturalism, whereby consideration of elemental desire involves commitment to the eudaimonistic society. This is then followed by a sublime discussion of key moments in the trajectory of Western philosophy, the tradition of which can now be seen to be based on what the author calls the unholy trinity of the epistemic fallacy or the reduction of being to knowledge, primal squeeze or the collapse of structure and alethic truth, and ontological monovalence. (shrink)

How engineers know, and act on that knowledge, has a profound impact on society. Consequently, the analysis of engineering knowledge is one of the central challenges for the philosophy of engineering. In this article, we present a thematic multidisciplinary conceptual survey of engineering epistemology and identify key areas of research that are still to be comprehensively investigated. Themes are organized based on a survey of engineering epistemology including research from history, sociology, philosophy, design theory, and engineering itself. Five major interrelated (...) themes are identified: the relationship between scientific and engineering knowledge, engineering knowledge as a distinct field of study, the social epistemology of engineering, the relationship between engineering knowledge and its products, and the cognitive aspects of engineering knowledge. We discuss areas of potential future research that are underdeveloped or “undone.”. (shrink)

How engineers know, and act on that knowledge, has a profound impact on society. Consequently, the analysis of engineering knowledge is one of the central challenges for the philosophy of engineering. In this article, we present a thematic multidisciplinary conceptual survey of engineering epistemology and identify key areas of research that are still to be comprehensively investigated. Themes are organized based on a survey of engineering epistemology including research from history, sociology, philosophy, design theory, and engineering itself. Five major interrelated (...) themes are identified: the relationship between scientific and engineering knowledge, engineering knowledge as a distinct field of study, the social epistemology of engineering, the relationship between engineering knowledge and its products, and the cognitive aspects of engineering knowledge. We discuss areas of potential future research that are underdeveloped or “undone.”. (shrink)

Kant’s theory of moral action faces a serious difficulty concerning motivation: how do commands of pure practical reason solely move human agents to perform moral actions? In his response, Kant claims that human agents perform moral actions out of a feeling of respect for the moral law. However, attempts to accommodate a feeling of respect into Kant’s rigorously rationalist ethical theory have led to two diverging strands of interpretation in the secondary literature: intellectualism and affectivism. Against this context, this paper (...) proposes an interpretation of Kantian moral motivation with an appropriate place for the notion of respect within it to resolve the motivational problem concerning moral actions. According to the model of Kantian moral motivation that this paper develops, motivation to act morally takes place in two sequential stages, each involving the positive role of respect as a motive. By arguing for a positive role of the feeling of respect in the process of moral motivation, this model aligns with the affectivist school of interpretation. (shrink)

In this book, Roy Bhaskar sets out to revindicate ontology, critiquing the reduction of being in favor of knowledge, which he calls the "epistemic fallacy".

This article is a step towards a rethinking of the emergence of the modern state in Europe. Traditionally, war has been viewed as the central mechanism of state formation. This approach claims that war caused the emergence of the modern state in two significant ways: 1) by consolidating the politically fragmented world of the middle ages through conquest; and 2) through the pressure of competition in a Darwinian international system, which forced the polities of Europe to create the bureaucratic structures (...) fundamental to the authority of the modern state. This article seeks to undermine the first of these mechanisms by showing that the territorial consolidation of Europe was a logical result of dynastic lordship. I seek to show that the consolidation of territory and authority into fewer and fewer hands was a direct consequence of dynastic successional practices and therefore that the emphasis on coercion in European political development has been overplayed. (shrink)

In their discussion paper of November 2020, Cooket alpresent a draft protocol for navigating circumstances in which emergency services are overwhelmed. Their paper suggests that COVID-related triage decisions should be based on clinical assessment, patient and family consultation, and a range of ethical considerations. In this response, we note that the protocol exhibits an ambiguity that is likely to result in irresolvable dilemmas when put into practice. This ambiguity is exemplified in the paper’s prime ethical imperative (to ‘save more lives (...) and more years of life’), which takes the form of an undefined conjunction whose practical implications are left unspecified. We see this ambiguity in the prime imperative as one manifestation of a broader set of tensions in the protocol. We show that the discipline of human rights provides an essential supplement to the ethical framework on which Cook and colleagues rely, providing a framework for understanding and working through triage dilemmas involving age, discrimination and equality. (shrink)

Since its original publication in 1979, The Possibility of Naturalism has been one of the most influential works in contemporary philosophy of science and social science. It is a cornerstone of the critical realist position, which is now widely seen as offering a viable alternative to move positivism and postmodernism. This revised edition includes a new foreword.

Since its inception in the 1970's, critical realism has grown to address a broad range of subjects, including economics, philosophy, science, and religion. It has also gone through a number of key evolutions that have changed its direction, and seen it develop into a complex and mature branch of philosophy. Critical Realism: A Brief Introduction, is the first book to look back over the entire field of critical realism in one concise and accessible volume. As the originator and chief exponent (...) of CR, Roy Bhaskar draws from his experience of countless introductory lectures, seminars, workshops and courses to give a definitive and compelling account of this increasingly influential, international and multi-disciplinary approach. Its eight chapters examine the following topics: Transcendental Realism and the Philosophy of Science Critical Naturalism and the Philosophy of Social Science Explanatory Critique and Ethics Language and Critical Discourse Analysis The Development of Critical Realism Interdisciplinarity and Applied Critical Realism Modernity, Theories of Science and Metacritique The Advantages of Critical Realism Everything from the definition of CR and its applicability to the social sciences, to explanations of dialectical critical realism and the philosophy of meta-reality are addressed in detail, making this the essential introduction for students of CR at all levels. (shrink)

Adequate reprogramming of cellular metabolism in response to stresses or suboptimal growth conditions involves a myriad of coordinated changes that serve to promote cell survival. As protein synthesis is an energetically expensive process, its regulation under stress is of critical importance. Reprogramming of messenger RNA (mRNA) translation involves well‐understood stress‐activated kinases that target components of translation initiation machinery, resulting in the robust inhibition of general translation and promotion of the translation of stress‐responsive proteins. Translational arrest of mRNAs also results in (...) the accumulation of transcripts in cytoplasmic foci called stress granules. Recent studies focus on the key roles of transfer RNA (tRNA) in stress‐induced translational reprogramming. These include stress‐specific regulation of tRNA pools, codon‐biased translation influenced by tRNA modifications, tRNA miscoding, and tRNA cleavage. In combination, signal transduction pathways and tRNA metabolism changes regulate translation during stress, resulting in adaptation and cell survival. This review examines molecular mechanisms that regulate protein synthesis in response to stress. (shrink)

The framing problematic of this dissertation is the political and epistemological relationship between metropolitan theory and post-colonial narrative. By providing multiple determinations to that problematic, I seek to situate the inventions of post-colonial identity. Using "detour" both as a privileged figure of contemporary theory and as the lived socio-historical experience of post-colonials, I examine the theoretical and political consequences using the former to translate the latter. Placing my own discourse at the limits of theory, I show that the predicament in (...) which contemporary theory finds itself is a result of the reduction of narrative to theory . ;I stage the negotiation between metropolitan theory and post-colonial narratives as an allegory of the post-colonial predicament. Finally, through a critique of certain post-colonial theorists , I plot the limits of the post-colonial space in the First World. I conclude that to invent the post-colonial space as a signifying space, we need to develop a poetics of retour which will be as complex and as ambiguous as the poetics of detour that the post-colonials have been living, narrating, and theorizing. ;Chapter I sets the theoretical context for posing the problem of post-colonial self-fashioning. In Chapter II, I sketch the trajectory of post-colonial detour through a close reading of V. S. Naipaul's The Mimic Men. In Chapter III, I interrogate Homi Bhabha's theory of cultural hybridity as a version of the poetics of detour. In Chapter IV, I offer a characterization of the predicament of theory. In the final chapter, I discuss the uses of theory by post-colonial intellectuals and offer a critique of their politics of cultural description and self-description. I argue that post-colonial theorists have evaded the question of inventing the post-colonial space as a signifying space by rewriting the narrative of their detour as a narrative of diplacement, as immigritude. (shrink)

Following on from Roy Bhaskarâe(tm)s first two books, A Realist Theory of Science and The Possibility of Naturalism, Scientific Realism and Human Emancipation, establishes the conception of social science as explanatoryâe"and thence emancipatoryâe"critique. Scientific Realism and Human Emancipation starts from an assessment of the impasse of contemporary accounts of science as stemming from an incomplete critique of positivism. It then proceeds to a systematic exposition of scientific realism in the form of transcendental realism, highlighting a conception of science as explanatory (...) of a structured, differentiated and changing world. Turning to the social domain, the book argues for a view of the social order as conditioned by, and emergent from, nature. Advocating a critical naturalism, the author shows how the transformational model of social activity together with the conception of social science as explanatory critique which it entails, resolves the divisions and dualisms besetting orthodox social and normative theory: between society and the individual, structure and agency, meaning and behavior, mind and body, reason and cause, fact and value, and theory and practice. The book then goes on to discuss the emancipatory implications of social science and sketches the nature of the depth investigation characteristically entailed. In the highly innovative third part of the book Roy Bhaskar completes his critique of positivism by developing a theory of philosophical discourse and ideology, on the basis of the transcendental realism and critical naturalism already developed, showing how positivism functions as a restrictive ideology of and for science and other social practices. (shrink)

Introduction: Critical realism, hegelian dialectic and the problems of philosophy preliminary considerations -- Objectives of the book -- Dialectic : an initial orientation -- Negation -- Four degrees of critical realism -- Prima facie objections to critical realism -- On the sources and general character of the hegelian dialectic -- On the immanent critique and limitations of the hegelian dialectic -- The fine structure of the hegelian dialectic -- Dialectic : the logic of absence, arguments, themes, perspectives, configurations -- Absence (...) -- Emergence -- Contradiction I : Hegel and Marx -- Contradiction II : misunderstandings -- On the materialist diffraction of dialectic -- Dialectical arguments and the unholy trinity -- Dialectical motifs : tina formation, mediation, concrete universality, etc -- On the generalized theory of the dialectical remark, the failure of detachment, and the presence of the past -- Dialectical critical naturalism -- Towards a real definition of dialectic -- Dialectical critical realism and the dialectic of freedom -- Ontology -- The dialectic of truth -- On the emergence and derivability of dialecticized transcendental realism -- 1m realism : non-identity -- 2e realism : negativity -- Space, time and tense -- Social science, explanatory critique, emancipatory axiology -- 3l realism : totality -- 4d realism : agency -- The dialectic of desire to freedom -- Dialectical critical realism and the dialectics of critical realism -- Metacritical dialectics : irrealism and its consequences -- Irrealism -- The problems of philosophy and their resolution -- Contradictions of the critical philosophy -- Dilemmas of the beautiful soul and the unhappy consciousness -- Master and slave : from dialectics of reconciliation to dialectics of liberation -- The metacritique of the hegelian dialectic -- Marxian dialectic i: the rational kernel in the mystical shell -- Marxian dialectic ii: the mystical shell in the rational kernel -- Metacritical dialectics : philosophical ideologies, their sublation and explanation -- The consequences of irrealism -- Diffracted and retotalized dialectics -- Dialectic as the pulse of freedom. (shrink)

In this paper, I aim to resolve the Frierson-Grenberg debate on the nature of Kant’s account of moral motivation that took place in the third issue of Con-textos Kantianos. In their respective interpretations, Frierson and Grenberg fail to accommodate the a priori status of moral feeling when incorporating it into Kant’s moral motivational structure. In response, I provide a novel transcendental interpretation – one that takes the a priori moral feeling both as an incentive of morality and as that which (...) conditions the possibility of morality in human agents. I argue that Kant developed the notion of moral feeling solely in order to resolve the problem of motivational skepticism concerning the moral law. Since this problem occurs as a part of Kant’s search for the supreme principle of morality, the notion of moral feeling becomes a part of both Kant’s moral motivational structure and his argument to justify the moral law. (shrink)

Is philosophy worth it? -- Explanation and the laws of nature -- Reference, truth, and meaning -- Causality, change, and emergence -- Making it happen (social agency) -- Dialectic -- Living well -- Dialectic critical realism -- Socrates and so on? -- Philosophy and the dialectic of emancipation -- Appendix: explaining philosophies.

A challenge to Kant’s less known duty of self-knowledge comes from his own firm view that it is impossible to know oneself. This paper resolves this problem by considering the duty of self-knowledge as involving the pursuit of knowledge of oneself as one appears in the empirical world. First, I argue that, although Kant places severe restrictions on the possibility of knowing oneself as one is, he admits the possibility of knowing oneself as one appears using methods from empirical anthropology. (...) Second, I show that empirical knowledge of oneself is fairly reliable and is, in fact, considered as morally significant from Kant’s moral anthropological perspective. Taking these points together, I conclude that Kant’s duty of self-knowledge exclusively entails the pursuit of empirical self-knowledge. (shrink)

This article discusses the importance of ‘public conscience’ in B. R. Ambedkar’s political thought. Ambedkar consistently defended public conscience as a democratic value in his writings and speeches. Public conscience referred to collective responsibility, social justice and the public deliberation of what constitutes the social good. Ambedkar consistently expressed the unequivocal belief that public conscience would bring about a moral transformation in Indian society through a collective ethical stance against all forms of social oppression. He conceptualized public conscience as a (...) method by which a democratic and ethical Indian society could come about and flourish. This article interrogates his ideas concerning public conscience through a detailed reading of his works, focusing particularly on his 1943 speech, Ranade, Gandhi and Jinnah. (shrink)

Now acknowledged as a classic in the philosophy of science, A Realist Theory of Science is one of the very few books to transform not only our understanding of science, but that of the nature of the world it studies. The book has inspired the multi-disciplinary and international movement of thought known as critical realism. Re-issued with a new introduction.

In _Philosophy and the Idea of Freedom_ Roy Bhaskar sets out to develop a critique of the work of Richard Rorty, who must be one of the most influential authors of recent decades. In a brilliant tour de force, Bhaskar shows how Rorty falls victim to the very epistemological problematic Rorty himself describes. Roy Bhaskar argues that Rorty’s account of science and knowledge is based on a half-truth. He sees the historicity of knowledge, but cannot sustain its (...) rationality or the reality of the objects it describes. The author further argues that Rorty’s problem-field replicates the Kantian resolution of the third antinomy: we are determined as material bodies, but free as discursive subjects. Rorty’s actualism makes human agency impossible. Developing his own critical realism, Bhaskar shows just where Rorty’s system comes unstuck, and how the philosophical problems to which it gives rise can be rationally resolved and explained. In this process Bhaskar utilizes his critique of Rorty to begin to elaborate his own alternative interpretation and critique of the philosophical conversation of the West. (shrink)

Between 1983 and 2006 there were two distinct sorts of historical writings on Southeast Asian medical history, with quite different emphases. Some historians focused on the history of medicine in national contexts—a practice that resulted in the neglect of larger socioeconomic factors such as migration—that affected the trajectory of pandemics. At the same time, pursuing a different line of thinking, another group of historians focused on the history of specific diseases from a demographic perspective. These two approaches led to very (...) different conclusions about the nature of epidemic disease and pandemics that have beset the region since the nineteenth century. Nevertheless, regional histories of health are neglected in Southeast Asian medical history in favor of either local, national, or global histories. In this essay, I argue that if historians of global health have forsaken the region in favor of the wider world, Southeast Asian historians have neglected the region in favor of the nation. What is missing in Southeast Asian medical history is a regional perspective that would help understand the ways in which pandemic responses are shaped by colonial, Cold War, or national concerns. Beginning 2019, some historians and political analysts trying to understand global pandemics have adopted a regional approach by treating, as a monolithic group, the ASEAN—the Association of Southeast Asian Nations, which is a regional grouping of Southeast Asian member states, established in 1967. By contrast, others explore specific geographic, political, or economic issues that have contributed to either the spread or containment of disease. In this regard, the COVID-19 crisis in Southeast Asia merits historical attention to comprehend the strengths and weaknesses of a regional approach. (shrink)

Since its original publication in 1979, The Possibility of Naturalism has been one of the most influential works in contemporary philosophy of science and social science. It is one of the cornerstones of the critical realist position, which is now widely seen as offering perhaps the only viable alternative to positivism and post positivism. This fourth edition contains a new foreword from Mervyn Hartwig, who is founding editor of the Journal of Critical Realism and editor and principal author of the (...) Dictionary of Critical Realism. (shrink)

In this radical book, Roy Bhaskar expands his philosophy of critical realism with an audacious re-synthesis of many aspects of Western and Eastern thought. Arguing that the existence of God provides the fundamental structure of the world, he renders plausible ideas of reincarnation, karma and moksha or liberation. Originally published in the year of the millennium, From East to West continues to be a groundbreaking and fundamental work within the critical realist tradition. Stimulating debate in ontology, epistemology, ethics, political (...) philosophy and the philosophy of religion, this book has been influential as a major new development in critical realism. This second edition contains a new introduction from Mervyn Hartwig, who is the founding editor of the _Journal of Critical Realism_ and editor and principal author of the _Dictionary of Critical Realism_. (shrink)

In her recent work, Nancy Folbre undertakes an ambitious effort: constructing an intersectional political economy that aims to identify the common mechanisms and logic underpinning the many wrongs that characterise capitalism. In this paper, we focus on what we deem the three fundamental theoretical pillars of her approach. First, she challenges the oppression/exploitation distinction within Marxian political economy and proposes a broader definition of exploitation that can take manifold forms. Second, she questions the Marxian concept of class, and emphasises the (...) variety of forms of subordination and exploitation related to social identities that cannot be reduced to Marxian classes. Finally, she advocates a more comprehensive notion of the economy beyond a focus on capitalist relations of production. It is difficult to understate the theoretical relevance of these claims, which highlight the importance of various contemporary forms of injustice—of which the exploitation of workers by capitalists is only one. As a complement to the Marxian theory of exploitation and class, Folbre’s approach would broaden our understanding of oppressive social relations. Yet as an alternative to Marxian political economy, it is ultimately unconvincing: a shift of emphasis to ‘manifold exploitations’, social groups, and the economy does not yield a gain in analytical insight but rather an impoverishment of our conceptual toolbox. The struggle against capitalism is different from the struggle against patriarchy and racism, even if the ultimate aim should be the removal of all structures of oppression and domination. (shrink)

Micro RNAs (miRNAs) have been shown to control many cellular processes including developmental timing in different organisms. The prediction that miRNAs are involved in regulating hox genes of flies and mouse is quite a recent idea and is supported by the finding that mir‐196 represses Hoxb8 gene expression. The non‐coding regions that encode these miRNAs are also conserved across species in the same way as other mechanisms that regulate expression of hox genes. On the contrary, until now no homeotic phenotype, (...) a hallmark of any hox gene mutation, had been associated with any hox miRNA. Recent work on bithorax complex miRNA (miR–iab‐4–5p) shows, for the first time, that miRNAs can lead to homeotic transformation. This miRNA regulates Ultrabithorax (Ubx) and results in the transformation of haltere to wing.1 This study unveils a new complexity and finesse to the regulation of hox gene expression pattern that is needed for determining the anteroposterior body axis in all bilaterians. BioEssays 28: 445–448, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

This series of interviews, conducted in the form of exchanges between Roy Bhaskar and Mervyn Hartwig, tells a riveting story of the formation and development of critical realism. Three intersecting and interweaving narratives unfold in the course of this unfinished story: the personal narrative of Roy Bhaskar, born of an Indian father and English mother, a child of post-war Britain and Indian partition and independence; the intellectual narrative of the emergence and growth of critical realism; and a world-historical (...) story, itself theorized by critical realism in its discussion of the development of modernity. This book gives an invaluable account of the development of critical realism, and its consolidation as a leading philosophy of our times. It takes us through the major moments of its formation, the principal objections to and controversies within critical realism, the establishment of its institutions, and considers its limits and future development. Special features of the book include discussion of the genesis of critical realism, and the origins and nature of the so-called dialectical and spiritual turns. The informal dialogical style of The Formation of Critical Realism makes it compelling reading and an invaluable source for students of critical realism as well as all those interested in the intellectual story of our times. (shrink)

Bortolotti’s Delusions and Other Irrational Beliefs defends the view that delusions are beliefs on a continuum with other beliefs. A different view is that delusions are more like illusions, that is, they arise from faulty perception. This view, which is not targeted by the book, makes it easier to explain why delusions are so alien and disabling but needs to appeal to forensic aspects of functioning.

Interdisciplinarity and Climate Change is a major new book addressing one of the most challenging questions of our time. Its unique standpoint is based on the recognition that effective and coherent interdisciplinarity is necessary to deal with the issue of climate change, and the multitude of linked phenomena which both constitute and connect to it. In the opening chapter, Roy Bhaskar makes use of the extensive resources of critical realism to articulate a comprehensive framework for multidisciplinarity, interdisciplinarity, transdisciplinarity and (...) cross-disciplinary understanding, one which duly takes account of ontological as well as epistemological considerations. Many of the subsequent chapters seek to show how this general approach can be used to make intellectual sense of the complex phenomena in and around the issue of climate change, including our response to it. Among the issues discussed, in a number of graphic and compelling studies, by a range of distinguished contributors, both activists and scholars, are: The dangers of reducing all environmental, energy and climate gas issues to questions of carbon dioxide emissions The problems of integrating natural and social scientific work and the perils of monodisciplinary tunnel vision The consequences of the neglect of issues of consumption in climate policy The desirability of a care-based ethics and of the integration of cultural considerations into climate policy The problem of relating theoretical knowledge to practical action in contemporary democratic societies Interdisciplinarity and Climate Change is essential reading for all serious students of the fight against climate change, the interactions between governmental bodies, and critical realism. (shrink)

In this concise text, Roy Bhaskar sets out to diagnose, explain and resolve the "problems of philosophy". _Plato Etc._ reviews all the main areas of the subject: the theory of knowledge and philosophy of science; the philosophy of logic and language; the philosophies of space, time and causality; the philosophy of the social and life sciences and of dialectic; ethics, politics and aesthetics; and the history and sociology of philosophy. Among the issues discussed are the problems of induction and (...) universals, the question of relativism, Heidegger’s "scandal of philosophy", the nature of moral truth and the conundrum of free will and determinism. The last two chapters consist of a synoptic account of the development of Western philosophy from the pre-Socratics to poststructuralism. _Plato Etc._ seeks to revindicate the philosophical project, and to demonstrate that the author’s "dialectical critical realism" has the categorical power to remedy the problem fields of philosophy. The book serves both as a critical introduction to philosophy and as an invaluable resource for the scholar. (shrink)

Increasing evidence indicates that extracellular vesicles (EVs) secreted from tumor cells play a key role in the overall progression of the disease state. EVs such as exosomes are secreted by a wide variety of cells and transport a varied population of proteins, lipids, DNA, and RNA species within the body. Gliomas constitute a significant proportion of all primary brain tumors and majority of brain malignancies. Glioblastoma multiforme (GBM) represents grade IV glioma and is associated with very poor prognosis despite the (...) cumulative advances in diagnostic procedures and treatment strategies. Here, the authors describe the progress in understanding the role of EVs, especially exosomes, in overall glioma progression, and how new research is unraveling the utilities of exosomes in glioma diagnostics and development of next‐generation therapeutic systems. Finally, based on an understanding of the latest scientific literature, a model for the possible working of therapeutic exosomes in glioma treatment is proposed. (shrink)

In a brilliant series of studies, Roy Bhaskar, the originator of the influential, multi-disciplinary and international philosophy of critical realism, presents for the first time in published form, his new philosophy of Meta-Reality. The philosophy of Meta-Reality confirms many aspects of the great philosophical traditions of the past, while correcting their one-sidedness and transcending their dualism and dichotomies, representing what is valid in them in a radically new way, apt for our contemporary times of global crisis.

The main objective of my dissertation is twofold: (i) to investigate how the problem of moral motivation occurs in Kant’s texts, and (ii) to examine how Kant’s account of moral feeling serves as an appropriate solution to it. First, I argue that the problem of moral motivation occurs in Kant’s texts as a skeptical problem concerning the motivational efficacy of practical reason. My view that this problem is integral to Kant’s main ethical project goes against a scholarly trend that dismisses (...) the philosophical significance of motivational skepticism in Kant’s moral theory. Second, I argue that Kant develops a peculiar notion of moral feeling in his Critique of Practical Reason primarily to resolve the problem of motivational skepticism about pure practical reason. In doing so, I regard the notion of moral feeling as an essential component of both Kant’s moral motivational structure and his justification of the moral law. This inclusion of moral feeling makes my interpretation a better alternative not only to standard transcendental interpretations of Kant’s account of moral motivation, but also to other kinds of interpretations proposed in the recent literature. (shrink)